
(1981). Many things have happened since then, of course, and everyone has their favorite list.
But looking back,
have several things, as listed below :
1. Cancer susceptibility genes. In 1981 we
knew that familial clustering of some cancers
occurred, for example, with colon cancer,
but the genes involved in this hadn’t been determined. The APC, BRCA-1,BRCA-2, and p53 inherited mutations, forexample, were not known at that time. Research
in this area has identified a number of genes involved in cancer susceptibility,andwithmoderncloningtechniques,more
are identified every few months.
2. The techniques of modern molecular biology...